3D printed liver expected in 2014

Approximately 18 people die every day waiting for an organ transplant. But that may change someday sooner than you think — thanks to 3D printing.

Advances in the 3D printing of human tissue have moved fast enough that San Diego-based bio-printing company Organovo now expects to unveil the world’s first printed organ, a human liver, in 2014.

Like other forms of 3D printing, bio-printing lays down layer after layer of material — in this case, live cells — to form a solid physical entity — in this case, human tissue. The major stumbling block in creating tissue continues to be manufacturing the vascular system needed to provide it with life-sustaining oxygen and nutrients.

The liver tissue model that Organovo plans to release next year is for research use only and will be used in the laboratory for medical studies and drug research. That’s important in its own right: Developing a new drug costs, on average, $1.2 billion and takes 12 years.

Organovo has as yet not released any information on possible future implantable organs. Any such initiative would have to undergo rigorous government review before being approved for clinical purposes.

The 3D liver tissue currently can be maintained in a functional state for about 40 days.

“It is too early to speculate on the breadth of applications that tissue engineering will ultimately deliver or on the efficacy that will be achieved,” says Mike Renard, VP, Commercial Operations, Organovo.

Dr. Ajay Sati.

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